Vitamin a Promotes the Repair of Mice Skeletal Muscle Injury through RARα

Vitamin A (VitA) is an important fat-soluble vitamin which plays role in cell growth and individual development. However, the effect of VitA on repair process muscle injury its molecular mechanism are still unclear. In this study, RA were first added to culture medium differentiated cells. We then detected differentiation marker proteins myotube fusion. Moreover, effects RARα expression nuclear translocation further examined. The results showed that significantly promoted C2C12, was increased. Furthermore, injected into skeletal mice. HE staining Western Blot could accelerate increase This study provides a theoretical basis for elucidating regulation VitA-mediated development therapeutic drugs diseases animals.